Immunoglobulin Heavy Chain Variable Region Gene Replacement as a Mechanism for Receptor Revision in Rheumatoid Arthritis Synovial Tissue B Lymphocytes

Mature B cells can alter their antibody repertoires by several mechanisms, including immunoglobulin heavy chain variable region (V(H)) replacement. This process changes the antigen combining site by replacing a portion of the original V(H)/diversity/heavy chain joining region (V(H)DJ(H)) rearrangeme...

Descripción completa

Detalles Bibliográficos
Autores principales: Itoh, Kenji, Meffre, Eric, Albesiano, Emilia, Farber, Andrew, Dines, David, Stein, Peter, Asnis, Stanley E., Furie, Richard A., Jain, Rita I., Chiorazzi, Nicholas
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195868/
https://www.ncbi.nlm.nih.gov/pubmed/11034605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195868/
https://www.ncbi.nlm.nih.gov/pubmed/11034605

Ejemplares similares