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Flice-Inhibitory Protein Is a Key Regulator of Germinal Center B Cell Apoptosis

Affinity maturation of the B cell response to antigen (Ag) takes place in the germinal centers (GCs) of secondary follicles. Two sequential molecular mechanisms underpin this process. First, the B cell repertoire is diversified through hypermutation of the immunoglobulin (Ig) variable region genes....

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Detalles Bibliográficos
Autores principales: Hennino, Ana, Bérard, Marion, Krammer, Peter H., Defrance, Thierry
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195905/
https://www.ncbi.nlm.nih.gov/pubmed/11181697