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Flice-Inhibitory Protein Is a Key Regulator of Germinal Center B Cell Apoptosis
Affinity maturation of the B cell response to antigen (Ag) takes place in the germinal centers (GCs) of secondary follicles. Two sequential molecular mechanisms underpin this process. First, the B cell repertoire is diversified through hypermutation of the immunoglobulin (Ig) variable region genes....
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195905/ https://www.ncbi.nlm.nih.gov/pubmed/11181697 |