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Overexpression of Cd40 Ligand in Murine Epidermis Results in Chronic Skin Inflammation and Systemic Autoimmunity

CD40–CD40 ligand (L) interactions play a pivotal role in immune-mediated inflammatory responses via the activation of antigen-presenting cells (APCs). To investigate the effects of continuous activation of resident tissue APCs, in this case the Langerhans cells (LCs) of the skin, CD40L expression wa...

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Detalles Bibliográficos
Autores principales: Mehling, Annette, Loser, Karin, Varga, Georg, Metze, Dieter, Luger, Thomas A., Schwarz, Thomas, Grabbe, Stephan, Beissert, Stefan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195942/
https://www.ncbi.nlm.nih.gov/pubmed/11535630