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Development of Spontaneous Autoimmune Peripheral Polyneuropathy in B7-2–Deficient Nod Mice

An increasing number of studies have documented the central role of T cell costimulation in autoimmunity. Here we show that the autoimmune diabetes-prone nonobese diabetic (NOD) mouse strain, deficient in B7-2 costimulation, is protected from diabetes but develops a spontaneous autoimmune peripheral...

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Detalles Bibliográficos
Autores principales: Salomon, Benoît, Rhee, Lesley, Bour-Jordan, Helene, Hsin, Honor, Montag, Anthony, Soliven, Betty, Arcella, Jennifer, Girvin, Ann M., Miller, Stephen D., Bluestone, Jeffrey A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195945/
https://www.ncbi.nlm.nih.gov/pubmed/11535635