Joining Chain–Expressing and–Nonexpressing B Cell Populations in the Mouse

The diphtheria toxin A chain (DTA) was gene targeted into the Joining chain (J chain) locus to create a mouse strain selecting against J chain–expressing cells, JDTA mice. Serum immunoglobulin (Ig)M and serum IgG were reduced six to eightfold, while serum IgA was elevated 14-fold in these mice. JDTA...

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Detalles Bibliográficos
Autores principales: Erlandsson, Lena, Akerblad, Peter, Vingsbo-Lundberg, Carina, Kallberg, Eva, Lycke, Nils, Leanderson, Tomas
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195946/
https://www.ncbi.nlm.nih.gov/pubmed/11535625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195946/
https://www.ncbi.nlm.nih.gov/pubmed/11535625

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