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Structural Features of Peptide Analogs of Human Histocompatibility Leukocyte Antigen Class I Epitopes That Are More Potent and Immunogenic than Wild-Type Peptide

Certain peptide analogs that carry substitutions at residues other than the main major histocompatibility complex anchors and are surprisingly much more antigenic than wild-type peptide (heteroclitic analogs). To date, it was unknown how frequently wild-type epitopes could be modified to obtain hete...

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Detalles Bibliográficos
Autores principales: Tangri, Shabnam, Ishioka, Glenn Y., Huang, Xiuqing, Sidney, John, Southwood, Scott, Fikes, John, Sette, Alessandro
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195959/
https://www.ncbi.nlm.nih.gov/pubmed/11560998