Protein Kinase Cε Is Required for Macrophage Activation and Defense Against Bacterial Infection

To assess directly the role of protein kinase C (PKC)ε in the immune system, we generated mice that carried a homozygous disruption of the PKCε locus. PKCε(−/)− animals appeared normal and were generally healthy, although female mice frequently developed a bacterial infection of the uterus. Macropha...

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Detalles Bibliográficos
Autores principales: Castrillo, Antonio, Pennington, Daniel J., Otto, Florian, Parker, Peter J., Owen, Michael J., Boscá, Lisardo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195971/
https://www.ncbi.nlm.nih.gov/pubmed/11696589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195971/
https://www.ncbi.nlm.nih.gov/pubmed/11696589

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