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Protein Kinase Cε Is Required for Macrophage Activation and Defense Against Bacterial Infection
To assess directly the role of protein kinase C (PKC)ε in the immune system, we generated mice that carried a homozygous disruption of the PKCε locus. PKCε(−/)− animals appeared normal and were generally healthy, although female mice frequently developed a bacterial infection of the uterus. Macropha...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2001
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195971/ https://www.ncbi.nlm.nih.gov/pubmed/11696589 |