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Identification of Cyclin B1 as a Shared Human Epithelial Tumor-Associated Antigen Recognized by T Cells

We eluted peptides from class I molecules of HLA-A2.1(+) breast adenocarcinoma and loaded reverse phase high-performance liquid chromatography (HPLC) fractions onto dendritic cells to prime naive CD8(+) T cells. Fractions that supported growth of tumor-specific cytotoxic T lymphocytes were analyzed...

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Detalles Bibliográficos
Autores principales: Kao, Henry, Marto, Jarrod A., Hoffmann, Thomas K., Shabanowitz, Jeffrey, Finkelstein, Sydney D., Whiteside, Theresa L., Hunt, Donald F., Finn, Olivera J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195974/
https://www.ncbi.nlm.nih.gov/pubmed/11696596