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Differential Roles of CD36 and αvβ5 Integrin in Photoreceptor Phagocytosis by the Retinal Pigment Epithelium

Retinal pigment epithelial (RPE) cells employ αvβ5 integrin and CD36 receptors to phagocytose photoreceptor outer segment fragments (OS). We explored special properties of RPE phagocytosis to identify the contribution of CD36 to RPE phagocytosis measuring effects of CD36 antibodies on OS binding and...

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Detalles Bibliográficos
Autores principales: Finnemann, Silvia C., Silverstein, Roy L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195987/
https://www.ncbi.nlm.nih.gov/pubmed/11696594