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Focal Activation of a Mutant Allele Defines the Role of Stem Cells in Mosaic Skin Disorders

Stem cells are crucial for the formation and maintenance of tissues and organs. The role of stem cells in the pathogenesis of mosaic skin disorders remains unclear. To study the molecular and cellular basis of mosaicism, we established a mouse model for the autosomal-dominant skin blistering disorde...

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Detalles Bibliográficos
Autores principales: Arin, Meral J., Longley, Mary Ann, Wang, Xiao-Jing, Roop, Dennis R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195990/
https://www.ncbi.nlm.nih.gov/pubmed/11157989