An Inducible Mouse Model for Epidermolysis Bullosa Simplex: Implications for Gene Therapy

The Dowling-Meara variant of epidermolysis bullosa simplex (EBS-DM) is a severe blistering disease inherited in an autosomal-dominant fashion. Here we report the generation of a mouse model that allows focal activation of a mutant keratin 14 allele in epidermal stem cells upon topical administration...

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Detalles Bibliográficos
Autores principales: Cao, Tongyu, Longley, Mary Ann, Wang, Xiao-Jing, Roop, Dennis R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195993/
https://www.ncbi.nlm.nih.gov/pubmed/11157990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195993/
https://www.ncbi.nlm.nih.gov/pubmed/11157990

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