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A Novel Neural Wiskott-Aldrich Syndrome Protein (N-Wasp) Binding Protein, Wish, Induces Arp2/3 Complex Activation Independent of Cdc42

We identified a novel adaptor protein that contains a Src homology (SH)3 domain, SH3 binding proline-rich sequences, and a leucine zipper-like motif and termed this protein WASP interacting SH3 protein (WISH). WISH is expressed predominantly in neural tissues and testis. It bound Ash/Grb2 through it...

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Detalles Bibliográficos
Autores principales: Fukuoka, Maiko, Suetsugu, Shiro, Miki, Hiroaki, Fukami, Kiyoko, Endo, Takeshi, Takenawa, Tadaomi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196001/
https://www.ncbi.nlm.nih.gov/pubmed/11157975