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Oligosaccharides of Hyaluronan Activate Dendritic Cells via Toll-like Receptor 4

Low molecular weight fragmentation products of the polysaccharide of Hyaluronic acid (sHA) produced during inflammation have been shown to be potent activators of immunocompetent cells such as dendritic cells (DCs) and macrophages. Here we report that sHA induces maturation of DCs via the Toll-like...

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Detalles Bibliográficos
Autores principales: Termeer, Christian, Benedix, Frauke, Sleeman, Jonathon, Fieber, Christina, Voith, Ursula, Ahrens, Thomas, Miyake, Kensuke, Freudenberg, Marina, Galanos, Christopher, Simon, Jan Christoph
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196009/
https://www.ncbi.nlm.nih.gov/pubmed/11781369
http://dx.doi.org/10.1084/jem.20001858