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P-Selectin Glycoprotein Ligand-1 (PSGL-1) on T Helper 1 but Not on T Helper 2 Cells Binds to P-Selectin and Supports Migration into Inflamed Skin

We have shown recently that mouse Th1 cells but not Th2 cells are selectively recruited into inflamed sites of a delayed-type hypersensitivity (DTH) reaction of the skin. This migration was blocked by monoclonal antibodies (mAb) against P- and E-selectin. Here we show that Th1 cells bind to P-select...

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Detalles Bibliográficos
Autores principales: Borges, Eric, Tietz, Wolfgang, Steegmaier, Martin, Moll, Thomas, Hallmann, Rupert, Hamann, Alf, Vestweber, Dietmar
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196023/
https://www.ncbi.nlm.nih.gov/pubmed/9053457