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Germinal Center Founder Cells Display Propensity for Apoptosis before Onset of Somatic Mutation

B lymphocytes undergo affinity maturation of their antigen receptors within germinal centers. These anatomical structures develop in secondary lymphoid organs from the clonal expansion of a few antigen-specific founder B cells, whose isolation and characterization are reported here. Human germinal c...

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Detalles Bibliográficos
Autores principales: Lebecque, Serge, de Bouteiller, Odette, Arpin, Christophe, Banchereau, Jacques, Liu, Yong-Jun
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196025/
https://www.ncbi.nlm.nih.gov/pubmed/9053456