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Targeted Expression of Major Histocompatibility Complex (MHC) Class II Molecules Demonstrates that Dendritic Cells Can Induce Negative but Not Positive Selection of Thymocytes In Vivo

It is well established that lymphoid dendritic cells (DC) play an important role in the immune system. Beside their role as potent inducers of primary T cell responses, DC seem to play a crucial part as major histocompatibility complex (MHC) class II(+) “interdigitating cells” in the thymus during t...

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Detalles Bibliográficos
Autores principales: Brocker, Thomas, Riedinger, Mireille, Karjalainen, Klaus
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196043/
https://www.ncbi.nlm.nih.gov/pubmed/9053454