Analysis of Protease Activity in Live Antigen-presenting Cells Shows Regulation of the Phagosomal Proteolytic Contents During Dendritic Cell Activation

Here, we describe a new approach designed to monitor the proteolytic activity of maturing phagosomes in live antigen-presenting cells. We find that an ingested particle sequentially encounters distinct protease activities during phagosomal maturation. Incorporation of active proteases into the phago...

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Detalles Bibliográficos
Autores principales: Lennon-Duménil, Ana-Maria, Bakker, Arnold H., Maehr, René, Fiebiger, Edda, Overkleeft, Herman S., Rosemblatt, Mario, Ploegh, Hidde L., Lagaudrière-Gesbert, Cécile
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196045/
https://www.ncbi.nlm.nih.gov/pubmed/12186844
http://dx.doi.org/10.1084/jem.20020327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196045/
https://www.ncbi.nlm.nih.gov/pubmed/12186844
http://dx.doi.org/10.1084/jem.20020327

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