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Reversal of Tumor-induced Dendritic Cell Paralysis by CpG Immunostimulatory Oligonucleotide and Anti–Interleukin 10 Receptor Antibody

Progressing tumors in man and mouse are often infiltrated by dendritic cells (DCs). Deficient antitumor immunity could be related to a lack of tumor-associated antigen (TAA) presentation by tumor-infiltrating DCs (TIDCs) or to a functional defect of TIDCs. Here we investigated the phenotype and func...

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Detalles Bibliográficos
Autores principales: Vicari, Alain P., Chiodoni, Claudia, Vaure, Céline, Aït-Yahia, Smina, Dercamp, Christophe, Matsos, Fabien, Reynard, Olivier, Taverne, Catherine, Merle, Philippe, Colombo, Mario P., O'Garra, Anne, Trinchieri, Giorgio, Caux, Christophe
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196048/
https://www.ncbi.nlm.nih.gov/pubmed/12186845
http://dx.doi.org/10.1084/jem.20020732