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Opsonization of Apoptotic Cells by Autologous iC3b Facilitates Clearance by Immature Dendritic Cells, Down-regulates DR and CD86, and Up-regulates CC Chemokine Receptor 7

Immature dendritic cells (iDCs) do not mature after uptake of apoptotic cells and may play a role in the induction of peripheral tolerance to self antigens derived from apoptotic material. The integrins, αvβ3, αvβ5, and the scavenger receptor, CD36, have been shown to mediate uptake of apoptotic cel...

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Detalles Bibliográficos
Autores principales: Verbovetski, Inna, Bychkov, Hila, Trahtemberg, Uriel, Shapira, Itzhak, Hareuveni, Mara, Ben-Tal, Ofira, Kutikov, Ina, Gill, Oranit, Mevorach, Dror
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196062/
https://www.ncbi.nlm.nih.gov/pubmed/12486098
http://dx.doi.org/10.1084/jem.20020263