Anti–DNA B Cells in MRL/lpr Mice Show Altered Differentiation and Editing Pattern

We have studied the regulation of anti–DNA B cells in transgenic mice with a heavy chain transgene (3H9H/56R). This transgene codes for a heavy chain that forms anti–double-stranded DNA (dsDNA) antibody when paired with most members of the endogenous Vκ repertoire, but certain L chains, referred to...

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Detalles Bibliográficos
Autores principales: Li, Yijin, Li, Hui, Ni, Dongyao, Weigert, Martin
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196070/
https://www.ncbi.nlm.nih.gov/pubmed/12486097
http://dx.doi.org/10.1084/jem.20021560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196070/
https://www.ncbi.nlm.nih.gov/pubmed/12486097
http://dx.doi.org/10.1084/jem.20021560

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