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Anti–DNA B Cells in MRL/lpr Mice Show Altered Differentiation and Editing Pattern
We have studied the regulation of anti–DNA B cells in transgenic mice with a heavy chain transgene (3H9H/56R). This transgene codes for a heavy chain that forms anti–double-stranded DNA (dsDNA) antibody when paired with most members of the endogenous Vκ repertoire, but certain L chains, referred to...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2002
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196070/ https://www.ncbi.nlm.nih.gov/pubmed/12486097 http://dx.doi.org/10.1084/jem.20021560 |