PD-1 Inhibits Antiviral Immunity at the Effector Phase in the Liver

Unlike naive T cells, effector T cells can be activated by either T cell receptor signal or costimulatory signal alone and therefore the absence of costimulatory molecules on tissue cells cannot explain the tolerance mechanism at the effector phase. Here we report that PD-L1, the ligand for the immu...

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Detalles Bibliográficos
Autores principales: Iwai, Yoshiko, Terawaki, Seigo, Ikegawa, Masaya, Okazaki, Taku, Honjo, Tasuku
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196084/
https://www.ncbi.nlm.nih.gov/pubmed/12847136
http://dx.doi.org/10.1084/jem.20022235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196084/
https://www.ncbi.nlm.nih.gov/pubmed/12847136
http://dx.doi.org/10.1084/jem.20022235

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