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PD-1 Inhibits Antiviral Immunity at the Effector Phase in the Liver
Unlike naive T cells, effector T cells can be activated by either T cell receptor signal or costimulatory signal alone and therefore the absence of costimulatory molecules on tissue cells cannot explain the tolerance mechanism at the effector phase. Here we report that PD-L1, the ligand for the immu...
Autores principales: | Iwai, Yoshiko, Terawaki, Seigo, Ikegawa, Masaya, Okazaki, Taku, Honjo, Tasuku |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196084/ https://www.ncbi.nlm.nih.gov/pubmed/12847136 http://dx.doi.org/10.1084/jem.20022235 |
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