Asynchronous Coreceptor Downregulation after Positive Thymic Selection: Prolonged Maintenance of the Double Positive State in CD8 Lineage Differentiation Due to Sustained Biosynthesis of the CD4 Coreceptor

In several experimental systems analyzing the generation of single positive (SP) thymocytes from double positive (DP) thymocytes, CD4 SP cells have been shown to appear before CD8 SP cells. This apparent temporal asymmetry in the maturation of CD4 SP and CD8 SP thymocytes could either be due to dive...

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Detalles Bibliográficos
Autores principales: Barthlott, Thomas, Kohler, Hubertus, Eichmann, Klaus
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196127/
https://www.ncbi.nlm.nih.gov/pubmed/9016884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196127/
https://www.ncbi.nlm.nih.gov/pubmed/9016884

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