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Induction of Apoptosis and T Helper 2 (Th2) Responses Correlates with Peptide Affinity for the Major Histocompatibility Complex in Self-reactive T Cell Receptor Transgenic Mice

Multiple sclerosis is an autoimmune disease thought to be mediated by CD4(+) T helper cells (Th). Experimental autoimmune encephalomyelitis is a rodent model of multiple sclerosis and has been used extensively to explore a variety of immunotherapies using soluble protein or peptide antigens. The und...

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Detalles Bibliográficos
Autores principales: Pearson, C.I., van Ewijk, W., McDevitt, H.O.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196136/
https://www.ncbi.nlm.nih.gov/pubmed/9034138