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The Immunodominant Antigen of an Ultraviolet-induced Regressor Tumor Is Generated by a Somatic Point Mutation in the DEAD Box Helicase p68

The genetic origins of CD8(+) T cell–recognized unique antigens to which mice respond when immunized with syngeneic tumor cells are unknown. The ultraviolet light-induced murine tumor 8101 expresses an H-2K(b)-restricted immunodominant antigen, A, that induces cytolytic CD8(+) T cells in vivo A(+) 8...

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Detalles Bibliográficos
Autores principales: Dubey, Purnima, Hendrickson, Ronald C., Meredith, Stephen C., Siegel, Christopher T., Shabanowitz, Jeffrey, Skipper, Jonathan C.A., Engelhard, Victor H., Hunt, Donald F., Schreiber, Hans
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196148/
https://www.ncbi.nlm.nih.gov/pubmed/9034148