Epitope Location in the Cryptococcus neoformans Capsule Is a Determinant of Antibody Efficacy

Monoclonal antibodies (mAbs) to the polysaccharide capsule of Cryptococcus neoformans can prolong survival in mice. However, the properties of antibodies that mediate protection are not fully understood. The IgM mAbs 12A1 and 13F1 originated from the same B cell and differ only by somatic mutations...

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Detalles Bibliográficos
Autores principales: Nussbaum, Gabriel, Cleare, Wendy, Casadevall, Arturo, Scharff, Matthew D., Valadon, Philippe
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196155/
https://www.ncbi.nlm.nih.gov/pubmed/9034147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196155/
https://www.ncbi.nlm.nih.gov/pubmed/9034147

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