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Role of the 5-Lipoxygenase–activating Protein (FLAP) in Murine Acute Inflammatory Responses

Leukotrienes are potent inflammatory mediators synthesized from arachidonic acid (AA) predominately by cells of myeloid origin. The synthesis of these lipids is believed to be dependent not only on the expression of the enzyme 5-lipoxygenase (5-LO), which catalyzes the first steps in the synthesis o...

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Detalles Bibliográficos
Autores principales: Byrum, Robert S., Goulet, Jennifer L., Griffiths, Richard J., Koller, Beverly H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196234/
https://www.ncbi.nlm.nih.gov/pubmed/9091580