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Regulation of  T Cell Receptor δ Gene Rearrangement by CBF/PEBP2

We have analyzed transgenic mice carrying versions of a human T cell receptor (TCR)-δ gene minilocus to study the developmental control of  VDJ (variable/diversity/joining) recombination. Previous data indicated that a 1.4-kb DNA fragment carrying the TCR-δ enhancer (E(δ)) efficiently activates mini...

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Detalles Bibliográficos
Autores principales: Lauzurica, Pilar, Zhong, Xiao-Ping, Krangel, Michael S., Roberts, Joseph L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196263/
https://www.ncbi.nlm.nih.gov/pubmed/9104806