Nonmitogenic Anti-CD3 Monoclonal Antibodies Deliver a Partial T Cell Receptor Signal and Induce Clonal Anergy

Anti-CD3 monoclonal antibodies (mAbs) are potent immunosuppressive agents used in clinical transplantation. However, the activation-related adverse side effects associated with these mAbs have prompted the development of less toxic nonmitogenic anti-CD3 mAb therapies. At present, the functional and...

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Detalles Bibliográficos
Autores principales: Smith, Judith A., Tso, J. Yun, Clark, Marcus R., Cole, Michael S., Bluestone, Jeffrey A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196281/
https://www.ncbi.nlm.nih.gov/pubmed/9126922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196281/
https://www.ncbi.nlm.nih.gov/pubmed/9126922

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