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Chronic Tumor Necrosis Factor Alters T Cell Responses by Attenuating T Cell Receptor Signaling

Repeated injections of adult mice with recombinant murine TNF prolong the survival of NZB/W F1 mice, and suppress type I insulin-dependent diabetes mellitus (IDDM) in nonobese diabetic (NOD) mice. To determine whether repeated TNF injections suppress T cell function in adult mice, we studied the res...

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Detalles Bibliográficos
Autores principales: Cope, Andrew P., Liblau, Roland S., Yang, Xiao-Dong, Congia, Mauro, Laudanna, Carlo, Schreiber, Robert D., Probert, Lesley, Kollias, George, McDevitt, Hugh O.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196294/
https://www.ncbi.nlm.nih.gov/pubmed/9151895