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Costimulation through B7-2 (CD86) Is Required for the Induction of a Lung Mucosal T Helper Cell 2 (TH2) Immune Response and Altered Airway Responsiveness

The recruitment of eosinophils into the airways after allergen exposure is dependent on interleukin (IL) 5 secreted from antigen-specific CD4(+) T cells of the T helper cell (Th) 2 subset. However, while it is established that costimulation through CD28 is required for TCR-mediated activation and IL...

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Detalles Bibliográficos
Autores principales: Tsuyuki, Shogo, Tsuyuki, Junko, Einsle, Karin, Kopf, Manfred, Coyle, Anthony J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196297/
https://www.ncbi.nlm.nih.gov/pubmed/9151904