The Active Site of ICP47, a Herpes Simplex Virus–encoded Inhibitor of the Major Histocompatibility Complex (MHC)-encoded Peptide Transporter Associated with Antigen Processing (TAP), Maps to the NH(2)-terminal 35 Residues

The herpes simplex virus (HSV) immediate early protein ICP47 inhibits the transporter associated with antigen processing (TAP)-dependent peptide translocation. As a consequence, empty major histocompatibility complex (MHC) class I molecules are retained in the endoplasmic reticulum and recognition o...

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Detalles Bibliográficos
Autores principales: Galocha, Begoña, Hill, Ann, Barnett, Barbara C., Dolan, Aidan, Raimondi, Alejandra, Cook, Richard F., Brunner, Joseph, McGeoch, Duncan J., Ploegh, Hidde L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196299/
https://www.ncbi.nlm.nih.gov/pubmed/9151894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196299/
https://www.ncbi.nlm.nih.gov/pubmed/9151894

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