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Pathogenesis of an Infectious Mononucleosis-like Disease Induced by a Murine γ-Herpesvirus: Role for a Viral Superantigen?

The murine γ-herpesvirus 68 has many similarities to EBV, and induces a syndrome comparable to infectious mononucleosis (IM). The frequency of activated CD8(+) T cells (CD62L(lo)) in the peripheral blood increased greater than fourfold by 21 d after infection of C57BL/6J (H-2(b)) mice, and remained...

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Detalles Bibliográficos
Autores principales: Tripp, Ralph A., Hamilton-Easton, Ann Marie, Cardin, Rhonda D., Nguyen, Phuong, Behm, Frederick G., Woodland, David L., Doherty, Peter C., Blackman, Marcia A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196306/
https://www.ncbi.nlm.nih.gov/pubmed/9151901