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HLA-A2.1–restricted Education and Cytolytic Activity of CD8(+) T Lymphocytes from β2 Microglobulin (β2m) HLA-A2.1 Monochain Transgenic H-2D(b) β2m Double Knockout Mice

Three different HLA-A2.1 monochains were engineered in which either the human or mouse β2-microglobulin (β2m) is covalently linked to the NH(2) terminus of the heavy chain by a 15– amino acid long peptide: HHH, entirely human, HHD, with the mouse H-2D(b) α3, transmembrane, and cytoplasmic domains, a...

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Detalles Bibliográficos
Autores principales: Pascolo, Steve, Bervas, Nathalie, Ure, Jan M., Smith, Austin G., Lemonnier, François A., Pérarnau, Béatrice
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196346/
https://www.ncbi.nlm.nih.gov/pubmed/9182675