Cargando…

Systemic T Cell–independent Tumor Immunity after Transplantation of Universal Receptor–modified Bone Marrow into SCID Mice

Gene modification of hematopoietic stem cells (HSC) with antigen-specific, chimeric, or “universal” immune receptors (URs) is a novel but untested form of targeted immunotherapy. A human immunodeficiency virus (HIV) envelope–specific UR consisting of the extracellular domain of human CD4 linked to t...

Descripción completa

Detalles Bibliográficos
Autores principales: Hege, Kristen M., Cooke, Keegan S., Finer, Mitchell H., Zsebo, Krisztina M., Roberts, Margo R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196383/
https://www.ncbi.nlm.nih.gov/pubmed/8976181