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Systemic T Cell–independent Tumor Immunity after Transplantation of Universal Receptor–modified Bone Marrow into SCID Mice
Gene modification of hematopoietic stem cells (HSC) with antigen-specific, chimeric, or “universal” immune receptors (URs) is a novel but untested form of targeted immunotherapy. A human immunodeficiency virus (HIV) envelope–specific UR consisting of the extracellular domain of human CD4 linked to t...
Autores principales: | Hege, Kristen M., Cooke, Keegan S., Finer, Mitchell H., Zsebo, Krisztina M., Roberts, Margo R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1996
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196383/ https://www.ncbi.nlm.nih.gov/pubmed/8976181 |
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