Killer Cell Inhibitory Receptor Recognition of Human Leukocyte Antigen (HLA) Class I Blocks Formation of a pp36/PLC-γ Signaling Complex in Human Natural Killer (NK) Cells

The killer cell inhibitory receptors (KIR) of human natural killer (NK) cells recognize human leukocyte antigen class I molecules and inhibit NK cell cytotoxicity through their interaction with protein tyrosine phosphatases (PTP). Here, we report that KIR recognition of class I ligands inhibits dist...

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Detalles Bibliográficos
Autores principales: Valiante, Nicholas M., Phillips, Joseph H., Lanier, Lewis L., Parham, Peter
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1996
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196393/
https://www.ncbi.nlm.nih.gov/pubmed/8976179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196393/
https://www.ncbi.nlm.nih.gov/pubmed/8976179

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