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Discovery of a novel murine keratin 6 (K6) isoform explains the absence of hair and nail defects in mice deficient for K6a and K6b

The murine genome is known to have two keratin 6 (K6) genes, mouse K6 (MK6)a and MK6b. These genes display a complex expression pattern with constitutive expression in the epithelia of oral mucosa, hair follicles, and nail beds. We generated mice deficient for both genes through embryonic stem cell...

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Detalles Bibliográficos
Autores principales: Wojcik, Sonja M., Longley, Mary A., Roop, Dennis R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196416/
https://www.ncbi.nlm.nih.gov/pubmed/11489919
http://dx.doi.org/10.1083/jcb.200102079