Activation of ARF6 by ARNO stimulates epithelial cell migration through downstream activation of both Rac1 and phospholipase D

Migration of epithelial cells is essential for tissue morphogenesis, wound healing, and metastasis of epithelial tumors. Here we show that ARNO, a guanine nucleotide exchange factor for ADP-ribosylation factor (ARF) GTPases, induces Madin-Darby canine kidney epithelial cells to develop broad lamelli...

Descripción completa

Detalles Bibliográficos
Autores principales: Santy, Lorraine C., Casanova, James E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196419/
https://www.ncbi.nlm.nih.gov/pubmed/11481345
http://dx.doi.org/10.1083/jcb.200104019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196419/
https://www.ncbi.nlm.nih.gov/pubmed/11481345
http://dx.doi.org/10.1083/jcb.200104019

Ejemplares similares