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Activation of ARF6 by ARNO stimulates epithelial cell migration through downstream activation of both Rac1 and phospholipase D

Migration of epithelial cells is essential for tissue morphogenesis, wound healing, and metastasis of epithelial tumors. Here we show that ARNO, a guanine nucleotide exchange factor for ADP-ribosylation factor (ARF) GTPases, induces Madin-Darby canine kidney epithelial cells to develop broad lamelli...

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Detalles Bibliográficos
Autores principales:	Santy, Lorraine C., Casanova, James E.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2001
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196419/ https://www.ncbi.nlm.nih.gov/pubmed/11481345 http://dx.doi.org/10.1083/jcb.200104019

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