Signaling from β(1)- and β(2)-adrenergic receptors is defined by differential interactions with PDE4

β(1)- and β(2)-adrenergic receptors (βARs) are highly homologous, yet they play clearly distinct roles in cardiac physiology and pathology. Myocyte contraction, for instance, is readily stimulated by β(1)AR but not β(2)AR signaling, and chronic stimulation of the two receptors has opposing effects o...

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Detalles Bibliográficos
Autores principales: Richter, Wito, Day, Peter, Agrawal, Rani, Bruss, Matthew D, Granier, Sébastien, Wang, Yvonne L, Rasmussen, Søren G F, Horner, Kathleen, Wang, Ping, Lei, Tao, Patterson, Andrew J, Kobilka, Brian, Conti, Marco
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196435/
https://www.ncbi.nlm.nih.gov/pubmed/18188154
http://dx.doi.org/10.1038/sj.emboj.7601968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196435/
https://www.ncbi.nlm.nih.gov/pubmed/18188154
http://dx.doi.org/10.1038/sj.emboj.7601968

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