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The AP2 binding site of synaptotagmin 1 is not an internalization signal but a regulator of endocytosis
One characteristic linking members of the synaptotagmin family to endocytosis is their ability to bind the heterotetrameric AP2 complex via their C2B domain. By using CD4/synaptotagmin 1 chimeras, we found that the internalization signal of synaptotagmin 1 lies at the extreme COOH-terminus of the pr...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2001
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196445/ https://www.ncbi.nlm.nih.gov/pubmed/11502761 http://dx.doi.org/10.1083/jcb.200103040 |