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Comparisons of CapG and gelsolin-null macrophages: demonstration of a unique role for CapG in receptor-mediated ruffling, phagocytosis, and vesicle rocketing

Capping the barbed ends of actin filaments is a critical step for regulating actin-based motility in nonmuscle cells. The in vivo function of CapG, a calcium-sensitive barbed end capping protein and member of the gelsolin/villin family, has been assessed using a null Capg allele engineered into mice...

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Detalles Bibliográficos
Autores principales: Witke, Walter, Li, Wei, Kwiatkowski, David J., Southwick, Frederick S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196452/
https://www.ncbi.nlm.nih.gov/pubmed/11514591
http://dx.doi.org/10.1083/jcb.200101113