v-Src phosphorylation of connexin 43 on Tyr247 and Tyr265 disrupts gap junctional communication

The mechanism by which v-Src disrupts connexin (Cx)43 intercellular gap junctional communication (GJC) is not clear. In this study, we determined that Tyr247 (Y247) and the previously identified Tyr265 (Y265) site of Cx43 were the primary phosphorylation targets for activated Src in vitro. We establ...

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Detalles Bibliográficos
Autores principales: Lin, Rui, Warn-Cramer, Bonnie J., Kurata, Wendy E., Lau, Alan F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196463/
https://www.ncbi.nlm.nih.gov/pubmed/11514593
http://dx.doi.org/10.1083/jcb.200102027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196463/
https://www.ncbi.nlm.nih.gov/pubmed/11514593
http://dx.doi.org/10.1083/jcb.200102027

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