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v-Src phosphorylation of connexin 43 on Tyr247 and Tyr265 disrupts gap junctional communication
The mechanism by which v-Src disrupts connexin (Cx)43 intercellular gap junctional communication (GJC) is not clear. In this study, we determined that Tyr247 (Y247) and the previously identified Tyr265 (Y265) site of Cx43 were the primary phosphorylation targets for activated Src in vitro. We establ...
Autores principales: | Lin, Rui, Warn-Cramer, Bonnie J., Kurata, Wendy E., Lau, Alan F. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196463/ https://www.ncbi.nlm.nih.gov/pubmed/11514593 http://dx.doi.org/10.1083/jcb.200102027 |
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