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Multiple cadherin extracellular repeats mediate homophilic binding and adhesion

The extracellular homophilic-binding domain of the cadherins consists of 5 cadherin repeats (EC1–EC5). Studies on cadherin specificity have implicated the NH(2)-terminal EC1 domain in the homophilic binding interaction, but the roles of the other extracellular cadherin (EC) domains have not been eva...

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Detalles Bibliográficos
Autores principales: Chappuis-Flament, Sophie, Wong, Ellen, Hicks, Les D., Kay, Cyril M., Gumbiner, Barry M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196848/
https://www.ncbi.nlm.nih.gov/pubmed/11449003
http://dx.doi.org/10.1083/jcb.200103143