Targeted ablation of NrCAM or ankyrin-B results in disorganized lens fibers leading to cataract formation

The NgCAM-related cell adhesion molecule (NrCAM) is an immunoglobulin superfamily member of the L1 subgroup that interacts intracellularly with ankyrins. We reveal that the absence of NrCAM causes the formation of mature cataracts in the mouse, whereas significant pathfinding errors of commissural a...

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Detalles Bibliográficos
Autores principales: Moré, Margret I., Kirsch, Frank-P., Rathjen, Fritz G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196853/
https://www.ncbi.nlm.nih.gov/pubmed/11449000
http://dx.doi.org/10.1083/jcb.200104038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196853/
https://www.ncbi.nlm.nih.gov/pubmed/11449000
http://dx.doi.org/10.1083/jcb.200104038

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